Welcome to the newly revamped Key Developments, now twice weekly and with non-COVID news. Right now, it’s actually still just COVID news, but we’ll be slowly morphing it into something broader as we go.
There are over 27.7 million global cases. Cases have grown around the world by over 1.9 million since last week; global case growth is accelerating. There have been over 900,000 total deaths. We are approaching the very grim milestone of 1 million dead. There are over 6.5 million cases in the US. There have been over 193,000 deaths in the US. The death rate is trending down in the US. India is ramping up in daily case growth, eclipsing all other countries in new cases per day. India is also ramping up in daily deaths:
— Eric Topol (@EricTopol) September 7, 2020
Oxford/AstraZenica vaccine trials are on hold after reports of a serious adverse event that could be a vaccine reaction. The details of the reaction have not been released but there is word that the patient should recover. The pause may delay the release of the vaccine, but the single event is unlikely to derail the whole project.
A cold-weather COVID-19 resurgence is anticipated by many epidemiologists, and some warn that true second waves could hit areas that were already badly affected before. Fall peaks are likely to be worse than previous ones.
The Sturgis Motorcycle Rally may have caused 250,000 cases. You read that right:
New analysis on Covid spread triggered by Sturgis event and implicated in the current epidemic in South Dakota. The estimates in this paper, if confirmed, would place Sturgis as the largest studied super spreading event in U.S. https://t.co/cNiTTs3Ilz
— Scott Gottlieb, MD (@ScottGottliebMD) September 8, 2020
Here’s some visuals on the Dakotas that back up the Sturgis assertion:
The Dakotas now lead the US in number of new infections per million people. pic.twitter.com/dw5QQFsOg9
— Eric Topol (@EricTopol) September 6, 2020
Dentists are seeing a huge uptick in cracked teeth. The culprit? Pandemic-induced stress. People are clenching their teeth at night, creating micro-fractures which predispose to cracking.
Prolonged gastrointestinal infections can occur with COVID-19. The virus may be present in the gut longer than it is present in the respiratory tract:
New study: Long term gut infectionhttps://t.co/kdwVPwr7wD
— Yaneer Bar-Yam (@yaneerbaryam) September 7, 2020
There’s more evidence that far-UVC light can kill the pandemic virus:
REPORT: Far-UVC light inactivates SARS-CoV-2 in seconds. Low dose far-UVC, thought to be safe for humans, could disinfect indoors, even w/people in the room (as opposed to typical UV which harms eyes/skin so can only be used when people aren't around 1/2 https://t.co/IMr4QscWiY
— Dr. Ali Nouri (@AliNouriPhD) September 6, 2020
7,000 health care workers have died from COVID-19, with an inordinate burden of these deaths occurring in Mexico:
Globally more than 7000 health care workers are dead from #coronavirus, including 1320 in Mexico, more than any country. Analysis from Amnesty Internat'l. Other hard-hit countries: the US, 1,077 HCW deaths; the UK, 649; Brazil, 634; Russia, 631 & India 573 https://t.co/xjeAHrAXER pic.twitter.com/wGUHGYRXTz
— delthia ricks 🔬 (@DelthiaRicks) September 6, 2020
Multiple vaccine makers have signed a pledge to maintain safety and not capitulate to political pressure to make shortcuts during the vaccine trial process. This is an important move to secure public trust in the safety of the vaccines we so desperately need. In addition, Dr. Moncef Slaoui says that phase 3 results are a necessity before approval and distribution. He’s an advisor to Operation Warp Speed.
So this is great (sarcasm, dear reader):
A common North American mouse can catch and spread the coronavirus in labs, studies show https://t.co/pxFhkQp67P
— delthia ricks 🔬 (@DelthiaRicks) September 3, 2020
There were no serious adverse reactions from the Russian vaccine trials, but before we interpret this Lancet piece too concretely, understand that these trials were not randomized and there was no control arm with either formulation. Large phase 3 trials are still planned for the Russian vaccines.
Pfizer might have results out as early as October. Its phase 3 vaccine trial began in July.